The short answer
There are fewer medications here than brand names suggest. Six approved products, built from four molecules — and where one molecule carries two brand names, it is the same drug approved for two different uses.
The full list
| Product | Molecule | Approved for | Form | Self-pay from |
|---|---|---|---|---|
| Wegovy | semaglutide | chronic weight management | weekly injection or daily tablet | $149 |
| Zepbound | tirzepatide | chronic weight management | weekly injection | $299 |
| Foundayo | orforglipron | chronic weight management | daily tablet | $149 |
| Ozempic | semaglutide | type 2 diabetes | weekly injection | $349 |
| Mounjaro | tirzepatide | type 2 diabetes | weekly injection | $499 |
| Rybelsus | semaglutide | type 2 diabetes | daily tablet | — |
| Trulicity | dulaglutide | type 2 diabetes | weekly injection | — |
| Victoza | liraglutide | type 2 diabetes | daily injection | — |
| Saxenda | liraglutide | chronic weight management | daily injection | — |
| Byetta | exenatide | type 2 diabetes | twice-daily injection | — |
That last column is the manufacturer’s own direct-purchase price, which is only one of the ways any of these is actually bought. Insurance, the Medicare Bridge programme and telehealth memberships arrive at different numbers for the same molecule, and the membership fee is the part usually left out of the sum. We total them route by route in what each route adds up to.
What each page covers
- Wegovy (semaglutide)The weight-management form of semaglutide, and the only product in the class currently sold both as a weekly injection and as a daily tablet.
- Zepbound (tirzepatide)Tirzepatide for weight management, and the product with the largest mean weight reduction in the trial table below. It is also the only GLP-1 medication approved for obstructive sleep apnoea in adults with obesity.
- Foundayo (orforglipron)Orforglipron — a non-peptide small molecule rather than a peptide, which is why it is the one tablet with no food or water timing restriction.
- Ozempic (semaglutide)The type 2 diabetes form of semaglutide, and the product whose brand name became shorthand for the entire class.
- Mounjaro (tirzepatide)The type 2 diabetes form of tirzepatide, which acts at a second receptor (GIP) as well as the GLP-1 receptor.
- Rybelsus (semaglutide)Oral semaglutide for type 2 diabetes — the first tablet in the class, and the reason a GLP-1 pill was possible at all.
- Trulicity (dulaglutide)The once-weekly injection that led this class before semaglutide arrived, approved for type 2 diabetes rather than weight management — and, like Victoza, carrying a cardiovascular risk-reduction indication that the newer weight-management products do not.
- Victoza (liraglutide)Liraglutide for type 2 diabetes, taken once daily rather than weekly. Daily dosing is the main practical reason the weekly products displaced it.
- Saxenda (liraglutide)The weight-management form of liraglutide, injected once daily at a 3 mg dose. It is the only one of the older agonists approved for the reason most readers of this site are here.
- Byetta (exenatide)Exenatide, injected twice daily within 60 minutes before the two main meals — the oldest dosing schedule in the class, and the clearest illustration of what weekly dosing replaced.
What these pages deliberately leave out
Side-effect rates, contraindications, dosing schedules and interactions are on each product’s FDA-approved label, published on DailyMed. We do not reproduce them, because a drug page that looks complete but was assembled second-hand is more dangerous than one that is visibly partial. Those subjects are covered at the level of the class, in side effects, dosing and titration, and how these medications work.
Sources
Each source below supports specific statements on this page. We cite the strongest available authority and verify against the current version before publishing.
- FDA-approved prescribing information (drug labels)DailyMed, U.S. National Library of MedicineSupports: The approved indication and dosage form for every product listed, and the labelled detail these pages deliberately do not reproduce.
- Drug approvals, labeling and safety communicationsU.S. Food & Drug AdministrationSupports: Approval status for each product, checkable in Drugs@FDA and the Orange Book.
This page is general education, not medical advice. Talk to your own healthcare provider about your situation before starting, stopping, or changing any medication.